|
KMID : 0191120120270070818
|
|
Journal of Korean Medical Science
2012 Volume.27 No. 7 p.818 ~ p.821
|
|
|
Methimazole-Induced Bullous Systemic Lupus Erythematosus: A Case Report
|
|
Seo Ji-Yeon
Byun Hee-Jin
Cho Kwang-Hyun
Lee Eun-Bong
|
|
|
Abstract
|
|
|
|
Bullous systemic lupus erythematosus (SLE) is a kind of LE-non-specific bullous skin disease that is rarely induced by a medication. We describe the first case of bullous SLE to develop after administration of methimazole. A 31-yr-old woman presented with generalized erythematous patches, multiple bullae, arthralgia, fever, conjunctivitis, and hemolytic anemia. Biopsy of her bulla showed linear deposition of lgG, lgA, C3, fibrinogen, and C1q at dermo-epidermal junction. She was diagnosed as bullous SLE and treated with prednisolone, dapsone, hydroxychloroquine, and methotrexate. Our experience suggests that SLE should be considered as a differential diagnosis when bullous skin lesions develop in patients being treated for hyperthyroidism.
|
|
|
KEYWORD
|
|
|
Bullous Systemic Lupus Erythematosus, Drug-Induced Lupus Erythematosus, Methimazole, Graves Disease
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
    
|
|